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BIOTOOL-CHF - BIOmarker based diagnostic TOOLkit to personalize pharmacological approaches in congestive heart failure

Call for proposal: HORIZON-HLTH-2022-TOOL-11
Role: Partner
Start date: - End date:
Type of funding: International
Responsible of the project: Prof.ssa Marianna Adamo
Department: Department of Medicine and Surgery, Radiology and Public Health

ABSTRACT

BIOTOOL-CHF

Paving the way for more efficient heart failure treatment and management

In Europe, 6.5 million people battle chronic heart failure (HF), the leading cause of adult hospitalisation with a 5-year mortality rate of 70 %. Current diagnostics for HF are inadequate, leading to ineffective use of diuretics, a cornerstone for symptom relief. The EU-funded BIOTOOL-CHF project aims to revolutionise care with validated biomarkers, an AI-based congestion and prognosis predictor, a decision-making tool for diuretic management and a point-of-care diagnostic. This approach promises to usher in a new era of personalised HF management, optimising existing pharmaceuticals and reducing re-hospitalisations. This innovative approach not only transforms HF management but also sets the stage for personalised strategies in treating HF with reduced ejection fraction.

PARTICIPANTS

  • IRCCS Azienda Ospedaliero Universitaria di Bologna (Coordinator), Italiy
  • University Medical Center Groningen, Netherlands;
  • Università degli Studi di Brescia, Italy;
  • Region Stockholm - Karolinska University Hospital, Sweden;
  • Assistance publique hopitaux de Paris, France;
  • National and Kapodistrian University of Athens, Greece;
  • University Medical Center Ljubljana, Slovenia;
  • Germans Trias i Pujol Research Institute, Spain;
  • INCLIVA Foundation, Spain;
  • KU Leuven - Katholieke Universiteit Leuven, Belgium;
  • Region Hovedstaden, Denmark;
  • ALMA MATER STUDIORUM - University of Bologna, Italy;
  • Onassios Cardiac Surgery Center, Greece;
  • Institut national de la santé et de la recherche médicale, France;
  • Predict4Health, France;
  • European Clinical Research Infrastructure Network, France;
  • Istituto Superiore di Sanità, Italiy;
  • Tinexta Innovation Hub; Italy;
  • University Hospital Schleswig-Holstein, Germany;
  • AISC APS - Italian Association of Heart Failure Patients and Cardiovascular Prevention, Germany;
  • I.M.A. Industria Macchine Automatiche S.p.A., Italy;
  • Erasmus University Rotterdam, Netherlands;
  • Fondazione per il tuo cuore ONLUS, Italy;
  • University of Applied Sciences and Arts Northwestern Switzerland, Switzerland

Total project costs/EU contribution: € 9 600 663,00

EU contribution assigned to UniBS: € 364.270,00

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