Pubblicazioni

2021

Basnet RM, Zizioli D, Muscò A, Finazzi D, Sigala S, Rossini E, Tobia C, Guerra J, Presta M, Memo M. Caffeine Inhibits Direct and Indirect Angiogenesis in Zebrafish Embryos Int J Mol Sci. 2021 May 3;22(9):4856. doi: 10.3390/ijms22094856. PMID: 34063734 Free PMC article.

Rossini E, Bosatta V, Abate A, Fragni M, Salvi V, Basnet RM, Zizioli D, Bosisio D, Piovani G, Valcamonico F, Mirabella G, Berruti A, Memo M, Sigala S. Cisplatin Cytotoxicity in Human Testicular Germ Cell Tumor Cell Lines Is Enhanced by the CDK4/6 Inhibitor Palbociclib. Clin Genitourin Cancer. 2021 Feb 8:S1558-7673(21)00029-X. doi: 10.1016/j.clgc.2021.01.006.PMID: 33676835

Zizioli D, Bernardi S, Varinelli M, Farina M, Mignani L, Bosio K, Finazzi D, Monti E, Polverelli N, Malagola M, Borsani E, Borsani G, Russo D. Development of BCR-ABL1 Transgenic Zebrafish Model Reproducing Chronic Myeloid Leukemia (CML) Like-Disease and Providing a New Insight into CML Mechanisms Cells. 2021 Feb 19;10(2):445. doi: 10.3390/cells10020445. PMID: 33669758 Free PMC article.

Laquatra C, Sanchez-Martin C, Dinarello A, Cannino G, Minervini G, Moroni E, Schiavone M, Tosatto S, Argenton F, Colombo G, Bernardi P, Masgras I, Rasola A. HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia. Cell Death Dis. 2021 May 1;12(5):434. doi: 10.1038/s41419-021-03716-6.

Stocco A, Smolina N, Sabatelli P, Šileikytė J, Artusi E, Mouly V, Cohen M, Forte M, Schiavone M and Bernardi P. Treatment with a triazole inhibitor of the mitochondrial permeability transition pore fully corrects the pathology of sapje zebrafish lacking dystrophin. Pharmacol Res. 2021 Mar;165:105421. doi: 10.1016/j.phrs.2021.105421.

2020

Guerra J, Chiodelli P, Tobia C, Gerri C, Presta M. Cancers (Basel). Long-Pentraxin 3 Affects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System.2020 Jul 1;12(7):1756. doi: 10.3390/cancers12071756.PMID: 3263030

Mignani L, Zizioli D, Borsani G, Monti E, Finazzi D The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos. Front Cell Dev Biol.2020 Dec 23; 8:596069.doi:10.3389/fcell.2020.596069.2020.PMID:  33425903

Khatri D, Mignani L, Zizioli D, Ritelli M, Monti E, Finazzi D. Abnormal Vasculature Development in Zebrafish Embryos with Reduced Expression of Pantothenate Kinase 2 Gene Bull Exp Biol Med. 2020 Nov;170(1):58-63. doi: 10.1007/s10517-020-05004-3. Epub 2020 Nov 25 PMID: 33237527

Belleri M, Paganini G, Coltrini D, Ronca R, Zizioli D, Corsini M, Barbieri A, Grillo E, Calza S, Bresciani R, Maiorano E, Mastropasqua MG, Annese T, Giacomini A, Ribatti D, Casas J, Levade T, Fabrias G, Presta M. β-Galactosylceramidase Promotes Melanoma Growth via Modulation of Ceramide Metabolism. Cancer Res. 2020 Nov 15;80(22):5011-5023. doi: 10.1158/0008-5472.CAN-19-3382. Epub 2020 Sep 30. PMID: 32998995

Carraro M, Jones K, Sartori G, Schiavone M, Antonucci S, Kucharczyk R, di Rago JP, Franchin C, Arrigoni G, Forte M, Bernardi P.The Unique Cysteine of F-ATP Synthase OSCP Subunit Participates in Modulation of the Permeability Transition Pore. Cell Rep. 2020 Sep 1;32(9):108095. doi: 10.1016/j.celrep.2020.108095.

Bano L, Kiel M, Sales G, Doxey AC, Mansfield MJ, Wami HT, Schiavone M, Rossetto O, Pirazzini M, Dobrindt U, Montecucco C. Genome Sequence of the Fish Brain Bacterium Clostridium tarantellae. Microbiol Resour Announc. 2020 Apr 16;9(16):e01575-19. doi: 10.1128/MRA.01575-19.

Nawaz MI, Rezzola S, Tobia C, Coltrini D, Belleri M, Mitola S, Corsini M, Sandomenico A, Caporale A, Ruvo M, Presta M. D-Peptide analogues of Boc-Phe-Leu-Phe-Leu-Phe-COOH induce neovascularization via endothelial N-formyl peptide receptor 3.Angiogenesis. 2020 Aug;23(3):357-369. doi: 10.1007/s10456-020-09714-0. Epub 2020 Mar 9.PMID: 32152757

Ronca R, Ghedini GC, Maccarinelli F, Sacco A, Locatelli SL, Foglio E, Taranto S, Grillo E, Matarazzo S, Castelli R, Paganini G, Desantis V, Cattane N, Cattaneo A, Mor M, Carlo-Stella C, Belotti A, Roccaro AM, Presta M, Giacomini A. FGF Trapping Inhibits Multiple Myeloma Growth through c-Myc Degradation-Induced Mitochondrial Oxidative Stress. Cancer Res. 2020 Jun 1;80(11):2340-2354. doi: 10.1158/0008-5472.CAN-19-2714. Epub 2020 Feb 24.

2019

Tobia C, Chiodelli P, Barbieri A, Buraschi S, Ferrari E, Mitola S, Borsani G, Guerra J, Presta M. Atypical Chemokine Receptor 3 Generates Guidance Cues for CXCL12-Mediated Endothelial Cell Migratio. Front Immunol. 2019 May 15;10:1092. doi: 10.3389/fimmu.2019.01092 PMID: 31156639 Free PMC article.

Gianoncelli A, Guarienti M, Fragni M, Bertuzzi M, Rossini E, Abate A, Basnet R.M, Zizioli D, Bono F, Terzolo M, Memo M, Berruti A, Sigala S. Adrenocortical Carcinoma Xenograft in Zebrafish Embryos as a Model to Study the In Vivo Cytotoxicity of Abiraterone Acetate.  Endocrinology 2019 Nov 1;160(11):2620-2629. doi: 10.1210/en.2019-00152.

Basnet R.M, Zizioli D, Taweedet S, Finazzi D and Memo M. Zebrafish Larvae as a Behavioral Model in Neuropharmacol Biomedicines 2019, 7 (1), 23; https://doi.org/10.3390/biomedicines7010023

Zizioli D, Mione M, Varinelli M, Malagola M, Bernardi S, Alghisi E, Borsani G, Finazzi D, Monti E, Presta M, Russo D. Zebrafish disease models in hematology: Highlights on biological and translational impact. Biochim Biophys Acta Mol Basis Dis. 2019 Mar 1;1865(3):620-633.doi:10.1016/j.bbadis.2018.12.015. Epub 2018 Dec 26. Review PMID:30593895

Šileikytė J, Devereaux J, de Jong J, Schiavone M, Jones K, Nilsen A, Bernardi P, Forte M, Cohen MS. Second-Generation Inhibitors of the Mitochondrial Permeability Transition Pore with Improved Plasma Stability. ChemMedChem. 2019 Oct 17;14(20):1771-1782. doi: 10.1002/cmdc.201900376.

Rezzola S, Ronca R, Loda A, Nawaz MI, Tobia C, Paganini G, Maccarinelli F, Giacomini A, Semeraro F, Mor M, Presta M. The Autocrine FGF/FGFR System in both Skin and Uveal Melanoma: FGF Trapping as a Possible Therapeutic Approach. Cancers (Basel). 2019 Sep 4;11(9):1305. doi: 10.3390/cancers11091305.

2018

Pagani F, Trivedi A, Khatri D, Zizioli D, Garrafa E, Mitola S, Finazzi D. Silencing of pantothenate kinase 2 reduces endothelial cell angiogenesis. Mol Med Rep. 2018 Nov;18(5):4739-4746. doi: 10.3892/mmr.2018.9480

Khatri D, Zizioli D, Trivedi A, Borsani G, Monti E, Finazzi D. Overexpression of Human Mutant PANK2 Proteins Affects Development and Motor Behavior of Zebrafish Embryos. Neuromolecular Med. 2018 Aug 23. doi: 10.1007/s12017-018-8508-8

Codenotti S, Poli M, Asperti M, Zizioli D, Marampon F, Fanzani A. Cell growth potential drives ferroptosis susceptibility in rhabdomyosarcoma and myoblast cell lines. J Cancer. Res Clin Oncol. 2018 Sep;144(9): 1717-1730.doi:10.1007/s00432-018-2699-0. Epub 2018 Jul 3.

Giorgio V, Schiavone M, Galber C, Carini M, Da Ros T, Petronilli V, Argenton F, Carelli V, Acosta Lopez MJ, Salviati L, Prato M, Bernardi P. The idebenone metabolite QS10 restores electron transfer in complex I and coenzyme Q defects. Biochim Biophys Acta Bioenerg. 2018 Sep;1859(9):901-908. doi: 10.1016/j.bbabio.2018.04.006.

Nawaz IM, Chiodelli P, Rezzola S, Paganini G, Corsini M, Lodola A, Di Ianni A, Mor M, Presta M. N-tert-butyloxycarbonyl-Phe-Leu-Phe-Leu-Phe (BOC2) inhibits the angiogenic activity of heparin-binding growth factors. Angiogenesis. 2018 Feb;21(1):47-59. doi: 10.1007/s10456-017-9581-6. Epub 2017 Oct 13.

2017

R.M.Basnet, D.Zizioli, M.Guarienti, D.Finazzi and M.Memo Methylxanthines induce structural and functional alterations of the cardiac system in zebrafish embryos. BMC Pharmacology and Toxicology (2017), vol18:72 ISSN:2050-6511 doi.org/10.1186/s40360-017-0179-9

V.Ravasio,E.Damiati, D.Zizioli, F.Orizio, E.Giacopuzzi, M.Manzoni, R.Bresciani, G. Borsani and Eugenio Monti (2017) Genomic and biochemical characterization of sialic acid acetylesterase (siae) in zebrafish. GLYCOBIOLOGY,vol 2,10, p. 938–946 ISSN:0959-6658, doi:10.1093/glycob/cwx068

D.Zizioli, C.Geumann, M.Kratzke, R.Mishra, G.Borsani, D.Finazzi, E.Candiello and P.Schu γ2 and γ1AP-1 complexes: different essential functions and regulatory mechanisms in clathrin-dependent protein sorting. EUROPEAN JOURNAL OF CELL BIOLOGY (2017) June pg 356-368

Schiavone M, Zulian A, Menazza S, Petronilli V, Argenton F, Merlini L, Sabatelli P, Bernardi P. Alisporivir rescues defective mitochondrial respiration in Duchenne muscular dystrophy. Pharmacol Res. 2017 Nov;125(Pt B):122-131. doi: 10.1016/j.phrs.2017.09.001.

Facchinello N, Tarifeño-Saldivia E, Grisan E, Schiavone M, Peron M, Mongera A, Ek O, Schmitner N, Meyer D, Peers B, Tiso N, Argenton F. Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration. Sci Rep. 2017 Aug 29;7(1):9605. doi: 10.1038/s41598-017-09867-x.

Giorgio V, Burchell V, Schiavone M, Bassot C, Minervini G, Petronilli V, Argenton F, Forte M, Tosatto S, Lippe G, Bernardi P. Ca2+ binding to F-ATP synthase β subunit triggers the mitochondrial permeability transition. EMBO Rep. 2017 Jul;18(7):1065-1076. doi: 10.15252/embr.201643354.

Basnet M.R, Guarienti M, Memo M Zebrafish Embryo as an In Vivo Model for Behavioral and Pharmacological Characterization of Methylxanthine Drugs, 2017 Int J Mol Sci Mar 9;18(3):596. doi: 10.3390/ijms18030596
2016

D.Khatri, D.Zizioli, N.Tiso, N.Facchinello, S.Vezzoli, A.Giagnoncelli, M.Memo, E.Monti, G.Borsani and D.Finazzi (2016) Down-regulation of coasy, the gene associated with NBIA-VI, reduces Bmp signaling, perturbs dorso-ventral patterning and alters neuronal development in zebrafish. SCIENTIFIC REPORTS, (2016) vol 6, ISSN: 2045-2332 doi:10.1038/srep37660

D.Zizioli, N.Tiso, A.Guglielmi, C.Saraceno, G.Busolin, R.Giuliani, D.Khatri, E.Monti, G. Borsani, F.Argenton and D.Finazzi. Knock-down of pantothenate kinase 2 severely affects the development of the nervous and vascular system in zebrafish, providing new insights into PKAN disease. NEUROBIOLOGY OF DISEASE, (2016) vol 85, p.35-48 ISSN: 0969-9961  doi.org/10.1016/j.nbd.2015.10.010016/J.hazmat 2014.07.017

Rezzola S, Paganini G, Semeraro F, Presta M, Tobia C. Zebrafish (Danio rerio) embryo as a platform for the identification of novel angiogenesis inhibitors of retinal vascular diseases. Biochim Biophys Acta. 2016 Jul;1862(7):1291-6. doi: 10.1016/j.bbadis.2016.04.009. Epub 2016 Apr 13. PMID: 27085972 Free article. Review

Consigli V, Guarienti M, Bilo F, Benassi L, Depero LE, Bontempi E, Presta M. Evaluation of the Biotoxicity of Tree Wood Ashes in Zebrafish Embryos.Zebrafish. 2016 Oct;13(5):449-55. doi: 10.1089/zeb.2016.1255. Epub 2016 Aug 3.PMID: 27487527

Zulian A, Schiavone M, Giorgio V, Bernardi P. Forty years later: Mitochondria as therapeutic targets in muscle diseases. Pharmacol Res. 2016 Nov;113(Pt A):563-573. doi: 10.1016/j.phrs.2016.09.043.

Facchinello N, Schiavone M, Vettori A, Argenton F, Tiso N. Monitoring Wnt Signaling in Zebrafish Using Fluorescent Biosensors. Methods Mol Biol. 2016;1481:81-94. doi: 10.1007/978-1-4939-6393-5_9.

Guarienti M, Cardozo SM, Borgese L, Lira GR, Depero LE, Bontempi E, Presta M. COSMOS-rice technology abrogates the biotoxic effects of municipal solid waste incinerator residues. Environ Pollut. 2016 Jul;214:713-721. doi: 10.1016/j.envpol.2016.04.053.