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Pubblicazioni – Publications

Pubblicazioni – Publications

 

2024

  • Segala A, Vezzoli M, Vetturi A, Garrafa E, Zanini B, Bottani E, Marullo M, Marconi S, Ricci C, Valerio A. A Mediterranean Diet-Oriented Intervention Rescues Impaired Blood Cell Bioenergetics in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease. Diagnostics (Basel). 2024 Sep 14;14(18):2041. doi: 10.3390/diagnostics14182041. PMID: 39335721
  • Monti M, Ferrari G, Grosso V, Missale F, Bugatti M, Cancila V, Zini S, Segala
    A, La Via L, Consoli F, Orlandi M, Valerio A, Tripodo C, Rossato M, Vermi W. Impaired activation of plasmacytoid dendritic cells via toll-like receptor 7/9 and STING is mediated by melanoma-derived immunosuppressive cytokines and metabolic drift. Front Immunol. 2024 Jan 3;14:1227648. doi:
    10.3389/fimmu.2023.1227648. PMID: 38239354

2023

  • Garrafa E, Segala A, Vezzoli M, Bottani E, Zanini B, Vetturi A, Bracale R, Ricci C, Valerio A. Mitochondrial Dysfunction in Peripheral Blood Mononuclear Cells as Novel Diagnostic Tools for Non-Alcoholic Fatty Liver Disease: Visualizing Relationships with Known and Potential Disease Biomarkers. Diagnostics (Basel). 2023 Jul 13;13(14):2363. doi: 10.3390/diagnostics13142363. PMID: 37510108

2022

  • Ragni M, Ruocco C, Tedesco L, Carruba MO, Valerio A, Nisoli E. An amino acid-defined diet impairs tumour growth in mice by promoting endoplasmic reticulum stress and mTOR inhibition. Mol Metab. 2022 Jun;60:101478. doi: 10.1016/j.molmet.2022.101478
  • Dolci S, Mannino L, Bottani E, Campanelli A, Di Chio M, Zorzin S, D'Arrigo G, Amenta A, Segala A, Paglia G, Denti V, Fumagalli G, Nisoli E, Valerio A, Verderio C, Martano G, Bifari F, Decimo I. Therapeutic induction of energy metabolism reduces neural tissue damage and increases microglia activation in severe spinal cord injury. Pharmacol Res. 2022 Apr;178:106149. doi: 10.1016/j.phrs.2022.106149 
  • Vliora M, Grillo E, Corsini M, Ravelli C, Nintou E, Karligiotou E, Flouris AD, Mitola S. Irisin regulates thermogenesis and lipolysis in 3T3-L1 adipocytes. Biochim Biophys Acta Gen Subj. 2022 Apr;1866(4):130085. doi: 10.1016/j.bbagen.2022.130085. PMID: 35016977
  • Chiodelli P, Coltrini D, Turati M, Cerasuolo M, Maccarinelli F, Rezzola S, Grillo E, Giacomini A, Taranto S, Mussi S, Ligresti A, Presta M, Ronca R. FGFR blockade by pemigatinib treats naïve and castration resistant prostate cancer. Cancer Lett. 2022 Feb 1;526:217-224. doi: 10.1016/j.canlet.2021.11.030. PMID: 34861311
  • Mignani L, Zizioli D, Khatri D, Facchinello N, Schiavone M, De Palma G, Finazzi D. Bi-Allelic Mutations in Zebrafish pank2 Gene Lead to Testicular Atrophy and Perturbed Behavior without Signs of Neurodegeneration. Int J Mol Sci. 2022 Oct 26;23(21):12914. doi: 10.3390/ijms232112914.

2021

  • La Spina M, Azzolini M, Salmaso A, Parrasia S, Galletta E, Schiavone M, Chrisam M, Mattarei A, Di Benedetto G, Ballabio A, Tiso N, Zoratti M, Biasutto L. Multiple Mechanisms Converging on Transcription Factor EB Activation by the Natural Phenol Pterostilbene. Oxid Med Cell Longev. 2021 Dec 28;2021:7658501. doi: 10.1155/2021/7658501.
  • Asperti M, Bellini S, Grillo E, Gryzik M, Cantamessa L, Ronca R, Maccarinelli F, Salvi A, De Petro G, Arosio P, Mitola S, Poli M. H-ferritin suppression and pronounced mitochondrial respiration make Hepatocellular Carcinoma cells sensitive to RSL3-induced ferroptosis. Free Radic Biol Med. 2021 Jun;169:294-303. doi: 10.1016/j.freeradbiomed.2021.04.024. PMID: 33892112
  • Grillo E, Corsini M, Ravelli C, Zammataro L, Bacci M, Morandi A, Monti E, Presta M, Mitola S. Expression of activated VEGFR2 by R1051Q mutation alters the energy metabolism of Sk-Mel-31 melanoma cells by increasing glutamine dependence. Cancer Lett. 2021 Jun 1;507:80-88. doi: 10.1016/j.canlet.2021.03.007. PMID: 33744390.
  • Laquatra C, Sanchez-Martin C, Dinarello A, Cannino G, Minervini G, Moroni E, Schiavone M, Tosatto S, Argenton F, Colombo G, Bernardi P, Masgras I, Rasola A. HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetics adaptations to hypoxia. Cell Death Dis. 2021 May 1;12(5):434. doi: 10.1038/s41419-021-03716-6.
  • Stocco A, Smolina N, Sabatelli P, Šileikytė J, Artusi E, Mouly V, Cohen M, Forte M, Schiavone M & Bernardi P. Treatment with a triazole inhibitor of the mitochondrial permeability transition pore fully corrects the pathology of sapje zebrafish lacking dystrophin. Pharmacol Res. 2021 Mar;165:105421. doi: 10.1016/j.phrs.2021.105421.
  • Romani C, Capoferri D, Grillo E, Silvestri M, Corsini M, Zanotti L, Todeschini P, Ravaggi A, Bignotti E, Odicino F, Sartori E, Calza S, Mitola S. The Claudin-Low Subtype of High-Grade Serous Ovarian Carcinoma Exhibits Stem Cell Features. Cancers (Basel). 2021 Feb 22;13(4):906. doi: 10.3390/cancers13040906. PMID: 33671478

2020

  • Ruocco C, Ragni M, Rossi F, Carullo P, Ghini V, Piscitelli F, Cutignano A, Manzo E, Ioris RM, Bontems F, Tedesco L, Greco CM, Pino A, Severi I, Liu D, Ceddia RP, Ponzoni L, Tenori L, Rizzetto L, Scholz M, Tuohy K, Bifari F, Di Marzo V, Luchinat C, Carruba MO, Cinti S, Decimo I, Condorelli G, Coppari R, Collins S, Valerio A, Nisoli E. Manipulation of Dietary Amino Acids Prevents and Reverses Obesity in Mice Through Multiple Mechanisms That Modulate Energy Homeostasis. Diabetes. 2020 Nov;69(11):2324-2339. doi: 10.2337/db20-0489. 
  • Bifari F, Dolci S, Bottani E, Pino A, Di Chio M, Zorzin S, Ragni M, Zamfir RG, Brunetti D, Bardelli D, Delfino P, Cattaneo MG, Bordo R, Tedesco L, Rossi F, Bossolasco P, Corbo V, Fumagalli G, Nisoli E, Valerio A, Decimo I. Complete neural stem cell (NSC) neuronal differentiation requires a branched chain amino acids-induced persistent metabolic shift towards energy metabolism. Pharmacol Res. 2020 Aug;158:104863. doi: 10.1016/j.phrs.2020.104863.
  • Ronca R, Ghedini GC, Maccarinelli F, Sacco A, Locatelli SL, Foglio E, Taranto S, Grillo E, Matarazzo S, Castelli R, Paganini G, Desantis V, Cattane N, Cattaneo A, Mor M, Carlo-Stella C, Belotti A, Roccaro AM, Presta M, Giacomini A. FGF Trapping Inhibits Multiple Myeloma Growth through c-Myc Degradation-Induced Mitochondrial Oxidative Stress. Cancer Res. 2020 Jun 1;80(11):2340-2354. doi: 10.1158/0008-5472.CAN-19-2714. PMID: 32094301
  • Tedesco L, Rossi F, Ruocco C, Ragni M, Carruba MO, Valerio A, Nisoli E. Experimental evidence on the efficacy of two new metabolic modulators on mitochondrial biogenesis and function in mouse cardiomyocytes. J Popul Ther Clin Pharmacol. 2020, 27: e12–e21. DOI: 10.15586/jptcp.v27iSP2.740 
  • Bugiardini E, Bottani E, Marchet S, Poole OV, Beninca C, Horga A, Woodward C, Lam A, Hargreaves I, Chalasani A, Valerio A, Lamantea E, Venner K, Holton JL, Zeviani M, Houlden H, Quinlivan R, Lamperti C, Hanna MG, Pitceathly RDS. Expanding the molecular and phenotypic spectrum of truncating MT-ATP6 mutations. Neurol Genet. 2020 Feb;6(1):e381. 

2019

  • Faustini G, Marchesan E, Zonta L, Bono F, Bottani E, Longhena F, Ziviani E, Valerio A, Bellucci A. Alpha-Synuclein Preserves Mitochondrial Fusion and Function in Neuronal Cells. Oxid Med Cell Longev. 2019 Nov 23;2019:4246350. doi: 10.1155/2019/4246350. PMID: 31871549
  • Di Somma M, Schaafsma W, Grillo E, Vliora M, Dakou E, Corsini M, Ravelli C, Ronca R, Sakellariou P, Vanparijs J, Castro B, Mitola S. Natural Histogel-Based Bio-Scaffolds for Sustaining Angiogenesis in Beige Adipose Tissue. Cells. 2019 Nov 18;8(11):1457. doi: 10.3390/cells8111457. PMID: 31752157
  • Matarazzo S, Melocchi L, Rezzola S, Grillo E, Maccarinelli F, Giacomini A, Turati M, Taranto S, Zammataro L, Cerasuolo M, Bugatti M, Vermi W, Presta M, Ronca R. Long Pentraxin-3 Follows and Modulates Bladder Cancer Progression. Cancers (Basel). 2019 Aug 30;11(9):1277. doi: 10.3390/cancers11091277. PMID: 31480336


 

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